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AICAR (Acadesine)
Welcome to our dedicated AICAR catalog. Here you can buy genuine, lab-verified AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide / Acadesine) manufactured by ZPHC — an established leader in pharmaceutical peptide synthesis and metabolic compounds. Every batch is manufactured under strict cGMP quality standards, offering guaranteed HPLC-verified purity exceeding 98% in standardized multi-vial kits.
AICAR is an analog of adenosine monophosphate (AMP) that functions as a direct, cell-permeable activator of AMP-activated protein kinase (AMPK). Widely recognized as an "exercise mimetic," AICAR stimulates mitochondrial biogenesis, triggers GLUT4 glucose transporter translocation, and accelerates lipid oxidation directly inside skeletal muscle tissue. By shifting energy production toward fatty acid metabolism while preserving intramuscular glycogen, it delivers a massive increase in aerobic stamina, endurance threshold, and recovery capacity without cardiac strain.
Product Verification: Authentic ZPHC Lyophilized Vials vs. Unstable Liquid Solutions
It is essential for buyers to distinguish pharmaceutical-grade, freeze-dried ZPHC AICAR from unverified liquid preparations or generic research chemicals. AICAR is unstable in aqueous form over prolonged periods; pre-mixed liquid solutions degrade rapidly in transit, losing biological activity. Our inventory consists exclusively of vacuum-sealed, lyophilized powder vials engineered for reconstitution with bacteriostatic water, complete with individual scratch-off verification codes on every box.
ZPHC products can be verified using the official ZPHC Validation System at https://validation.zphc.com/
Compound Characteristics & Available Stock
| Parameter | Specification |
|---|---|
| Active Substance | AICAR (Acadesine / 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) |
| Manufacturer | ZPHC (Zhengzhou Pharmaceutical Co., Ltd.) |
| Molecular Formula | C9H14N4O5 (Vacuum-sealed lyophilized white powder) |
| Purity Rating | ≥ 98.5% (Verified via HPLC & Mass Spectrometry) |
| Biological Target | Direct Master AMPK Pathway Activator (Non-hormonal) |
| Active Half-Life | ~1 to 2 hours (Cellular signaling cascades remain active for 12–24 hours) |
| Stock Formats | • AICAR ZPHC – 250 mg (5 vials × 50 mg) — $79.00 |
AICAR vs. Cardarine (GW-501516) & Stenabolic (SR9009)
Evaluating the leading non-hormonal endurance compounds helps clarify their distinct cellular mechanisms and stacking applications:
| Compound | Primary Mechanism | Administration | Glycogen Sparing | HPTA Suppression |
|---|---|---|---|---|
| AICAR (Acadesine) | Direct AMPK kinase phosphorylation | Subcutaneous / Intramuscular | Extremely High (Switches muscle to fat oxidation) | Zero (Non-hormonal) |
| Cardarine (GW-501516) | PPAR-delta receptor agonist | Oral liquid / capsule | High (Increases oxidative capacity) | Zero (Non-hormonal) |
| Stenabolic (SR9009) | Rev-ErbA circadian agonist | Oral / Sublingual | Moderate (Metabolic rate increase) | Zero (Non-hormonal) |
| EPO (Erythropoietin) | Hematocrit / RBC production | Subcutaneous / Intravenous | Low (Oxygen delivery focus) | Zero (Affects hematology) |
Dosage Protocols, Reconstitution & Administration
Because AICAR directly upregulates cellular ATP production and glucose uptake, administration must align with training schedules:
- ZPHC 5 Vials × 50 mg Kit ($79.00): The 5-vial format provides 250mg total active compound, making it the ideal multi-week protocol kit. Reconstituting each 50mg vial as needed ensures that the remaining unmixed lyophilized vials maintain maximum stability and shelf life.
- Reconstitution Technique: Using a sterile syringe, slowly inject 1.0 ml or 2.0 ml of bacteriostatic water (BAC water) down the inner glass wall of a single 50mg vial. Allow the liquid to absorb into the powder cake. Swirl gently in circular motions until clear; never shake vigorously.
- Dosing Precision (with 2ml Dilution): Diluting one 50mg vial with 2.0 ml of BAC water yields 25 mg/ml (2.5 mg per 10 IU on a U-100 insulin syringe). A standard 10mg daily dose corresponds to 40 IU (0.4 ml).
- Administration Timing: Administer subcutaneously (into abdominal fat) or intramuscularly 30 to 60 minutes prior to intense cardio, endurance training, or competition. Typical cycles run for 4 to 6 weeks.
Stacking Synergy, Safety & Non-Hormonal Integration
AICAR operates outside the endocrine system, offering complete versatility in both male and female athletic protocols:
- Zero Endocrine Suppression: AICAR is completely non-androgenic and non-steroidal. It does not suppress the HPTA axis (LH and FSH), causes zero aromatization into estrogen, and requires no Post-Cycle Therapy (PCT).
- Endurance Synergy (The Cardarine Stack): AICAR forms an exceptional synergy when stacked with Cardarine (GW-501516). While Cardarine upregulates the genetic transcription of fat-burning genes via PPAR-δ, AICAR provides acute cellular AMPK activation, creating unmatched aerobic output and VO2 max support.
- Nutritional Management: Because AICAR significantly upregulates GLUT4 transporters and glucose uptake in muscle cells, users should maintain stable complex carbohydrate intake around heavy training sessions to prevent transient hypoglycemic dips.
Ordering, Shipping & Discreet Packaging FAQ
How are AICAR orders packaged for delivery?
All items are dispatched using strict, 100% discreet packaging protocols. Parcels are shipped in plain, unmarked, heavy-duty padded envelopes or neutral boxes. There are zero mentions of peptides, lab chemicals, compound names, or store details on the outer parcel label.
How can I verify that my ZPHC AICAR is original?
Every ZPHC box is sealed with a holographic security label featuring an individual scratch-off verification code. You can input this code directly into the official ZPHC verification portal at validation.zphc.com to authenticate genuine batch production.
What payment methods can I use at checkout?
We accept anonymous and instant cryptocurrency payments (Bitcoin, USDT, Ethereum) for complete transactional privacy, alongside selected secure digital payment gateways.
How quickly do orders dispatch and arrive?
Orders are processed within 48 business hours after payment confirmation. After the order is processed, a tracking number is provided. Delivery normally takes 15–17 days, with domestic delivery options available where applicable.